Original Article

PLATINO, a nine-year follow-up study of COPD in the city of São Paulo, Brazil: the problem of underdiagnosis

PLATINO, estudo de seguimento de nove anos sobre DPOC na cidade de São Paulo: o problema do subdiagnóstico

J Bras Pneumol.2014;40(1):30-37

Objective: To determine the underdiagnosis rate in new COPD cases at the end of a nine-year follow-up period-in the study designated "Projeto Latino-Americano de Investigação em Obstrução Pulmonar" (PLATINO, Latin-American Pulmonary Obstruction Investigation Project)-and compare that with the underdiagnosis rate during the initial phase of the study, as well as to identify the clinical features exhibited by the subjects who were not diagnosed until the end of the follow-up phase. Methods: The study population comprised the 1,000 residents of the city of São Paulo, Brazil, who took part in the PLATINO study. Of those, 613 participated in the follow-up phase, during which the subjects were assessed with the same instruments and equipment employed in the initial phase of the study. We used the chi-square test or the independent sample t-test to analyze the underdiagnosis rate and to identify the characteristics of the subjects who were not diagnosed until the end of the follow-up phase. Results: The underdiagnosis rate for new COPD cases at the end of the nine-year follow-up period was 70.0%. The underdiagnosis rate during the follow-up phase was 17.5% lower than that reported for the initial phase of the study. The subjects who were not diagnosed until the end of the follow-up phase presented with fewer respiratory symptoms, better pulmonary function, and less severe disease than did those previously diagnosed with COPD. Conclusions: The underdiagnosis rate for new COPD cases was lower in the follow-up phase of the study than in the initial phase. The subjects who were not diagnosed until the end of the follow-up phase of the PLATINO study presented with the same clinical profile as did those who were not diagnosed in the initial phase. These findings underscore the need for spirometry in order to confirm the diagnosis of COPD and provide early intervention.

Keywords: Pulmonary disease, chronic obstructive/diagnosis; Pulmonary disease, chronic obstructive/epidemiology; Spirometry.

Quality of Communication Questionnaire para pacientes com DPOC em cuidados paliativos: tradução e adaptação cultural para uso no Brasil

Flávia Del Castanhel1, Suely Grosseman2

J Bras Pneumol.2017;43(5):357-362

Lung donor profile in the state of São Paulo, Brazil, in 2006

Perfil do doador de pulmão disponibilizado no estado de São Paulo, Brasil, em 2006

Paulo Manuel Pêgo Fernandes, Marcos Naoyuki Samano, Jader Joel Machado Junqueira, Daniel Reis Waisberg, Gustavo Sousa Noleto, Fabio Biscegli Jatene

J Bras Pneumol.2008;34(7):497-505

Outcomes of tuberculosis treatment among inpatients and outpatients in the city of São Paulo, Brazil

Desfechos de tratamento de tuberculose em pacientes hospitalizados e não hospitalizados no município de São Paulo

Mirtes Cristina Telles Perrechi, Sandra Aparecida Ribeiro

J Bras Pneumol.2011;37(6):783-790

Epidemiological aspects of pleural tuberculosis in the state of São Paulo, Brazil (1998-2005)

Aspectos epidemiológicos da tuberculose pleural no estado de São Paulo (1998-2005)

Márcia Seiscento, Francisco Suso Vargas, Maria Josefa Penon Rujula, Sidney Bombarda, David Everson Uip, Vera Maria Nedes Galesi

J Bras Pneumol.2009;35(6):548-554

Factors associated with death by tuberculosis in the eastern part of São Paulo city, 2001

Fatores associados ao óbito por tuberculose na zona leste da cidade de São Paulo, 2001

Monica Hid Haddad Pelaquin, Rebeca Souza e Silva, Sandra Aparecida Ribeiro

J Bras Pneumol.2007;33(3):311-317

Smoking among physicians in a specific region of the greater metropolitan area of São Paulo

Tabagismo entre médicos da Região do ABC Paulista

Adriano Cesar Guazzelli, Mário Terra Filho, Elie Fiss

J Bras Pneumol.2005;31(6):516-522

Tuberculosis recurrence in a priority city in the state of São Paulo, Brazil

Recorrência de tuberculose em município prioritário do estado de São Paulo

Amadeu Antonio Vieira1,2, Danila Torres Leite3, Solange Adreoni2

J Bras Pneumol.2017;43(2):106-112

Ninety-day outcomes in patients diagnosed with COVID-19 in São Paulo, Brazil: a cohort study

Desfechos em 90 dias entre pacientes com diagnóstico de COVID-19 em São Paulo (SP): estudo de coorte

Renata Rego Lins Fumis1, Eduardo Leite Vieira Costa1,2, Bruno Martins Tomazini1,3, Leandro Utino Taniguchi1,4, Livia do Valle Costa1, Christian Valle Morinaga1, Marcia Martiniano de Sousa e Sá1, Luciano Cesar Pontes de Azevedo1,4, Teresa Cristina Nascimento1, Carla Bernardes Ledo1, Maura Salaroli de Oliveira1, Luiz Francisco Cardoso1, Laerte Pastore Junior1, José Mauro Vieira Junior1

J Bras Pneumol.2023;49(3):e20230056

Identifying malignant mesothelioma by a pathological survey using the São Paulo state hospital cancer registry, Brazil

Fabiola Del Carlo Bernardi 1, Eduardo Algranti2, Marisa Dolhnikoff3, Clóvis Antônio Lopes Pinto4, Ivanir Martins de Oliveira5, Ester Nei Aparecida Martins Coletta6, Eduardo Caetano Albino da Silva7, Adauto José Ferreira Nunes8, Donaldo Botelho Veneziano9, Carolina Terra de Moraes Luizaga10, Ricardo Luiz Lorenzi11, Diego Rodrigues Mendonça e Silva12, Thais Mauad3

J Bras Pneumol.2024;50(2):e20230343

Tuberculosis treatment: integration between hospitals and public health care clinics in the city of São Paulo, Brazil

Tratamento de tuberculose: integração entre assistência hospitalar e rede básica na cidade de São Paulo

Mirtes Cristina Telles Perrechi, Sandra Aparecida Ribeiro

J Bras Pneumol.2009;35(11):1100-1106

Epidemiological profile of lung tuberculosis infection and disease among cocaine users being treated in hospitals of São Paulo, Brazil

Perfil epidemiológico da tuberculose infecção e doença entre usuários de cocaína internados em serviços hospitalares da Grande São Paulo

Olavo Franco Ferreira Filho, Marilia Dalva Turchi, Ronaldo Laranjeiras, Adauto Castelo

J Bras Pneumol.2003;29(3):125-132

Descriptive study of the frequency of nontuberculous mycobacteria in the Baixada Santista region of the state of São Paulo, Brazil

Estudo descritivo da freqüência de micobactérias não tuberculosas na Baixada Santista

Liliana Aparecida Zamarioli, Andréa Gobetti Vieira Coelho, Clemira Martins Pereira, Ana Carolina Chiou Nascimento, Suely Yoko Mizuka Ueki, Erica Chimara

J Bras Pneumol.2008;34(8):590-594

University of São Paulo Reasons for Smoking Scale: a new tool for the evaluation of smoking motivation

Escala Razões para Fumar da Universidade de São Paulo: um novo instrumento para avaliar a motivação para fumar

Elisa Sebba Tosta de Souza, José Alexandre de Souza Crippa, Sonia Regina Pasian, José Antônio Baddini Martinez

J Bras Pneumol.2010;36(6):768-778

Special Article

Exploratory analysis of requests for authorization to dispense high-cost medication to COPD patients: the São Paulo

Análise exploratória de solicitações de autorização para dispensação de medicação de alto custo para portadores de DPOC:

Regina Maria Carvalho-Pinto11,a, Ingredy Tavares da Silva1,2,b, Lucas Yoshio Kido Navacchia1,c, Flavia Munhos Granja1,2,d, Gustavo Garcia Marques1,2,e, Telma de Cassia dos Santos Nery1,f, Frederico Leon Arrabal Fernandes1,g, Alberto Cukier1,h, Rafael Stelmach1,i

J Bras Pneumol.2019;45(6):e20180355

Original Article

Reasons for the admission, length of stay and type of discharge in tuberculosis hospitals in the State of São Paulo, Brazil - 1981 to 1995

Motivos e tempo de internação e o tipo de saída em hospitais de tuberculose do Estado de São Paulo, Brasil - 1981 a 1995

Péricles Alves Nogueira

J Bras Pneumol.2001;27(3):123-129

Brief Communication

Occurrence of influenza among patients hospitalized for suspicion of influenza A (H1N1) infection in 2010 at a sentinel hospital in São Paulo, Brazil

Ocorrência de influenza em pacientes hospitalizados com suspeita de infecção por influenza A (H1N1) em 2010 em um hospital sentinela na cidade de São Paulo

Thaís Boim Melchior, Sandra Baltazar Guatura, Clarice Neves Camargo, Aripuanã Sakurada Aranha Watanabe, Celso Granato, Nancy Bellei

J Bras Pneumol.2011;37(5):655-658

Original Article

Availability and use of noninvasive ventilation in the intensive care units of public, private and teaching hospitals in the greater metropolitan area of São Paulo, Brazil

Conhecimento da disponibilidade e sobre o uso da ventilação não invasiva em unidades de terapia intensiva de hospitais públicos, privados e de ensino da região metropolitana de São Paulo

Lara Maris Nápolis, Leila Mara Jeronimo, Danila Vieira Baldini, Michelle Pinheiro Machado, Virgínia Aparecida de Souza, Pedro Caruso

J Bras Pneumol.2006;32(1):29-34

Objective: To determine the availability of noninvasive positive-pressure ventilation equipment, as well as the level of expertise and familiarity of physicians, nurses and physiotherapists with noninvasive positive-pressure ventilation in the intensive care units of public, private and teaching hospitals in the greater metropolitan area of São Paulo, Brazil. Methods: On-site administration of questionnaires. Results: Noninvasive positive-pressure ventilation equipment was widely available and was more commonly found in private hospitals than in teaching hospitals. Such equipment was least available in public hospitals, in which the predominant method was the use of mechanical ventilators designed for invasive ventilation and adapted to noninvasive positive-pressure ventilation. In private hospitals, continuous flow ventilators were more common, whereas, in teaching hospitals, ventilators specifically designed for noninvasive ventilation were typically employed. All physiotherapists felt themselves capable of initiating noninvasive positive pressure ventilation, compared with 72.6% of physicians and 33.3% of nurses. Physicians and physiotherapists presented high percentages of correct answers when asked about the indications and contraindications for the use of noninvasive positive-pressure ventilation. Over a one year period, more physiotherapists read articles about noninvasive positive-pressure ventilation and participated in related classes than did physicians, who in turn did so more than did nurses. Conclusion: Noninvasive positive-pressure ventilation equipment is widely available in the greater metropolitan area of São Paulo, although differences exist among public, private and teaching hospitals in terms of the type of equipment used. Physicians and physiotherapists exhibited considerable knowledge regarding the indications and contraindications for the use of noninvasive positive-pressure ventilation. More physiotherapists felt themselves able to initiate noninvasive positive-pressure ventilation, and their knowledge of the subject was more current than was that of physicians or nurses.

Keywords: Ventilators, mechanical; Positive-pressure respiration/methods; Respiratory insuficiency; Intensive care units; Hospitals

Adverse effects of tuberculosis treatment: experience at an outpatient clinic of a teaching hospital in the city of São Paulo, Brazi

Efeitos adversos no tratamento da tuberculose: experiência em serviço ambulatorial de um hospital-escola na cidade de São Paulo

Denise Eri Onodera Vieira, Mauro Gomes

J Bras Pneumol.2008;34(12):1049-1055

Analysis of treatment outcomes related to the tuberculosis control program in the city of Campinas, in the state of São Paulo, Brazil

Análise do programa de controle da tuberculose em relação ao tratamento, em Campinas - SP

Helenice Bosco de Oliveira, Leticia Marin-León, Jovana Gardinali

J Bras Pneumol.2005;31(2):133-138

Background: Tuberculosis cure is dependent upon treatment adherence. Objective: To analyze the results of tuberculosis treatment in public health clinics in the city of Campinas, in the state of São Paulo, Brazil, during 2002. Method: From a cohort of 484 patients diagnosed with tuberculosis, we evaluated 436. Treatment outcomes were described for all patients, whether new patients or patients in retreatment, including those presenting the pulmonary form, with or without acquired immunodeficiency syndrome (AIDS) comorbidity. Results: The success rate was 68.6% (72.3% among non-AIDS patients and 57.6% among AIDS patients). Among new cases, the non-AIDS group presented a 2.2-times greater chance of presenting favorable results. In the AIDS group, no differences were observed between new patients and those in retreatment. Among the unfavorable outcomes, only lethality presented a difference (18.9% among AIDS patients and 8.0% among non-AIDS patients). In patients presenting the pulmonary form, the success rate was similar between those who were initially acid-fast bacilli positive and those who were not. Conclusion: The tuberculosis control program in Campinas presented low effectiveness. In comparison to the 2001 national cohort, success rates were higher for non-AIDS patients but lower for AIDS patients. The higher success rate among cases of tuberculosis without AIDS was primarily derived from the treatment of new cases. The unfavorable profile of tuberculosis patients co-infected with AIDS, characterized by the (18.9%) lethality and the (15.3%) noncompliance, were partially responsible for the lower success rate seen among such patients. It is notable that such high proportions of noncompliant patients were seen in a city providing easy access to treatment. In order to improve the program, medical teams should receive further training in supervised treatment, health education and techniques for interacting with patients, all of which will require considerable investment.

Keywords: Key words: Tuberculosis. Treatment Refusal. Retreatment. Acquired Immunodeficiency Syndrome. Comorbidity

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