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Role of the IL8 rs4073 polymorphism in central nervous system toxicity in patients receiving multidrug-resistant tuberculosis treatment

Papel do polimorfismo rs4073 do gene IL8 na toxicidade do sistema nervoso central em pacientes em tratamento para tuberculose multirresistente

Ibrahim Mohammed Badamasi1, Muktar Muhammad1, Aishat Ahmad Umar1, Umm-ayman Misbahu Madugu1, Muktar Ahmed Gadanya2, Isa Abubakar Aliyu3, Imam Malik Kabir3, Ibrahim Aliyu Umar4, Ochigbo Johnson5, Johnson Stanslas6

DOI: https://dx.doi.org/10.36416/1806-3756/e20230338

1. Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences – FBMS – College of Medicine, Bayero University, Kano, Kano, Nigeria.
2. Department of Community Medicine, Faculty of Clinical Sciences, Bayero University, Kano, Kano, Nigeria.
3. Department of Medical Laboratory Science, Faculty of Allied Health Sciences – FAHS – Bayero University, Kano, Kano, Nigeria.
4. Kano State TB and Leprosy Control Program, Kano State Ministry of Health, Kano, Nigeria.
5. Kano State Infectious Disease Hospital, Kano State Ministry of Health, Kano, Nigeria.
6. Pharmacotherapeutics Lab, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Recebido: 5 setembro 2023.
Aprovado: 1 novembro 2023.
Trabalho realizado no Kano State Infectious Disease Hospital, Kano State Ministry of Health, Kano, Nigeria.
Endereço para correspondência:
Ibrahim Mohammed Badamasi. Pharmacogenomic Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences – FBMS – College of Medicine, Bayero University, Kano, Kano State, Kano, Nigeria.
Tel.: 08037024135. E-mail: bimohammed.ana@buk.edu.ng
Johnson Stanslas. Pharmacotherapeutics Lab, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Tel.: +60 122670497. E-mail: jstanslas@yahoo.co.uk
Apoio financeiro: Este estudo recebeu apoio financeiro do Nigerian Tertiary Education Trust Fund (Fundo Fiduciário de Ensino Superior da Nigéria).

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