Frederico Leon Arrabal Fernandes, Vanessa Aparecida Leão Pavezi, Sérvulo Azevedo Dias Jr., Regina Maria Carvalho Pinto, Rafael Stelmach, Alberto Cukier

J Bras Pneumol.2010;36(2):181-189

6 - Competence of senior medical students in diagnosing tuberculosis based on chest X-rays

Competência de estudantes de medicina seniores na interpretação de radiografias de tórax para o diagnóstico de tuberculose

Vania Maria Carneiro da Silva, Ronir Raggio Luiz, Míriam Menna Barreto, Rosana Souza Rodrigues, Edson Marchiori

J Bras Pneumol.2010;36(2):190-196

7 - Effects of breathing exercises on breathing pattern and thoracoabdominal motion after gastroplasty

Efeitos de exercícios respiratórios sobre o padrão respiratório e movimento toracoabdominal após gastroplasti

Georgia Miranda Tomich, Danielle Corrêa França, Marco Túlio Costa Diniz, Raquel Rodrigues Britto, Rosana Ferreira Sampaio, Verônica Franco Parreira

J Bras Pneumol.2010;36(2):197-204

8 - Impact that positive reinforcement during spirometry has on the measurement of VC in healthy volunteers

Impacto da utilização de reforço positivo na mensuração da CV por espirometria em voluntários saudáveis

Vanessa Sales Logrado, Erili Mota Sena, Renato Júlio dos Santos Matos, Tássia Menezes Leite da Silva, Tuliane Ribeiro de Oliveira, Kristine Menezes Barberino Mendes, Kátia de Miranda Avena

J Bras Pneumol.2010;36(2):205-209

9 - Respiratory symptoms in charcoal production workers in the cities of Lindolfo Collor, Ivoti and Presidente Lucena, Brazil

Sintomas respiratórios em trabalhadores de carvoarias nos municípios de Lindolfo Collor, Ivoti e Presidente Lucena, RS

Rafael Machado de Souza, Fabiana Michelsen de Andrade, Angela Beatrice Dewes Moura, Paulo José Zimermann Teixeira

J Bras Pneumol.2010;36(2):

10 - Evaluation of hospitalized patients in terms of their knowledge related to smoking

Avaliação do conhecimento sobre tabagismo em pacientes internados

Suzana Erico Tanni, Nathalie Izumi Iritsu, Masaki Tani, Paula Angeleli Bueno de Camargo, Marina Gonçalves Elias Sampaio, Ilda Godoy, Irma Godoy

J Bras Pneumol.2010;36(2):218-223

11 - Drug resistance profile of Mycobacterium tuberculosis in the state of Mato Grosso do Sul, Brazil, 2000-2006

Perfil de resistência de Mycobacterium tuberculosis no estado de Mato Grosso do Sul, 2000-2006

Marli Marques, Eunice Atsuko Totumi Cunha, Antonio Ruffino-Netto, Sonia Maria de Oliveira Andrade

J Bras Pneumol.2010;36(2):224-231

Objective: To determine the drug resistance profile of Mycobacterium tuberculosis in the state of Mato Grosso do Sul, Brazil, between 2000 and 2006. Methods: Descriptive study of reported tuberculosis cases in the Brazilian Case Registry Database. We included only those cases in which M. tuberculosis culture was positive and sensitivity to drugs (rifampicin, isoniazid, streptomycin and ethambutol) was tested. Löwenstein-Jensen and Ogawa-Kudoh solid media were used for cultures, as was an automated liquid medium system. Sensitivity tests were based on the proportion method. Results: Among the 783 cases evaluated, males predominated (69.7%), as did patients in the 20-49 year age bracket (70%), a diagnosis of pulmonary tuberculosis (94.4%) and positive HIV serology (8.6%); 645 (82.4%) were new cases, and 138 (17.6%) had previously been treated. Resistance to at least one drug was found in 143 cases (18.3%). The primary resistance (PR) rate was, respectively, 8.1%, 1.6%, 2.8% and 12.4%, for monoresistance, multidrug resistance (MDR), other patterns of resistance and resistance to at least one drug, whereas the acquired resistance (AR) rate was 14.5%, 20.3%, 10.9% and 45.7%, respectively, and the combined resistance (CR) rate was 9.2%, 4.9%, 4.2% and 18.3%, respectively. In PR, streptomycin was the most common drug, whereas isoniazid was the most common in AR and CR (7.2% and 3.7%, respectively). Conclusions: These high levels of resistance undermine the efforts for tuberculosis control in Mato Grosso do Sul. Acquired MDR was 12.7 times more common than was primary MDR, demonstrating that the previous use of drug therapy is an indicator of resistance. These levels reflect the poor quality of the health care provided to these patients, showing the importance of using the directly observed treatment, short course strategy, as well as the need to perform cultures and sensitivity tests for the early diagnosis of drug resistance.

Keywords: Tuberculosis; Drug resistance, multiple; Mycobacterium tuberculosis.

12 - Adverse effects of the new tuberculosis treatment regimen recommended by the Brazilian Ministry of Health

Efeitos adversos causados pelo novo esquema de tratamento da tuberculose preconizado pelo Ministério da Saúde do Brasil

Ethel Leonor Noia Maciel, Letícia Molino Guidoni, Juliana Lopes Favero, David Jamil Hadad, Lucilia Pereira Molino, John L. Jonhson, Reynaldo Dietze

J Bras Pneumol.2010;36(2):232-238

Brief Communication

13 - Attitudes of Brazilian pulmonologists toward nicotine dependence: a national survey

Atitudes dos pneumologistas brasileiros em face da dependência de nicotina: inquérito nacional

Carlos Alberto de Assis Viegas, Antonio Gabriel Teles Valentim, Jaene Andrade Pacheco Amoras, Euler Junior Moreira Nascimento

J Bras Pneumol.2010;36(2):239-242

Special Article

14 - Tuberculosis in rheumatoid arthritis patients: the difficulty in making the diagnosis of latent infection

Tuberculose em pacientes com artrite reumatoide: a dificuldade no diagnóstico da forma latente

Daniela Graner Schuwartz Tannus Silva, Bruna Daniella de Souza Silva, Ana Paula Junqueira-Kipnis, Marcelo Fouad Rabahi

J Bras Pneumol.2010;36(2):243-251

Review Article

15 - The educational component in an integrated approach to bronchial asthma

El componente educativo en el abordaje integral del asma bronquial

María Paola Fasciglione, Claudia Elena Castañeiras

J Bras Pneumol.2010;36(2):252-259

Case Report

16 - Usefulness of chest CT in the diagnosis of pulmonary sequestration

A utilidade da TC de tórax no diagnóstico do sequestro pulmonar

José Gustavo Pugliese, Thiago Prudente Bártholo, Heron Teixeira Andrade dos Santos, Eduardo Haruo Saito, Cláudia Henrique da Costa, Rogério Rufino

J Bras Pneumol.2010;36(2):260-264

17 - Lung hyperinflation after single lung transplantation to treat emphysema

Hiperinsuflação pulmonar após transplante unilateral por enfisema

Marcos Naoyuki Samano, Jader Joel Machado Junqueira, Ricardo Henrique de Oliveira Braga Teixeira, Marlova Luzzi Caramori, Paulo Manuel Pêgo-Fernandes, Fabio Biscegli Jatene

J Bras Pneumol.2010;36(2):265-269

Letters to the Editor

18 - Selective digestive decontamination is superior to oropharyngeal chlorhexidine in preventing pneumonia and reducing mortality in critically ill patients

A descontaminação digestiva seletiva é superior à clorexidina via orofaringe na prevenção de pneumonia e na redução da mortalidade em pacientes criticamente enfermos

Luciano Silvestri, Hendrick K.F. van Saene, Liviano Folla, Marco Milanese

J Bras Pneumol.2010;36(2):270-273

Author's reply

19 - Resposta do autor

Simone Macedo Amaral, Antonieta de Queiróz Côrtes, Fábio Ramôa Pires

J Bras Pneumol.2010;36(2):272-

Letters to the Editor

20 - Classification of journals in the Qualis system: time to broaden the discussion

Classificação dos periódicos no sistema Qualis: é o momento de ampliar a discussão

Marli Maria Knorst

J Bras Pneumol.2010;36(2):274-

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Year 2010 - Volume 36 - Issue 2 (March/April)

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