Year 2003 - Volume 29 - Issue 4 (July/August)

Editorial

1 - Baixa estatura mas alta espirometria

Noé Zamel

J Bras Pneumol.2003;29(4):175-

2 - Monitoração da inflamação das vias aéreas na asma

Mark D. Inman

J Bras Pneumol.2003;29(4):176-

Original Article

3 - Questionnaire of quality of life in patients with primary hyperhidrosis

Questionário de qualidade de vida em pacientes com hiperidrose primária

José Ribas Milanez de Campos, Paulo Kauffman, Eduardo de Campos Werebe, Laert Oliveira Andrade Filho, Sergio Kuzniek, Nelson Wolosker, Fábio Biscegli Jatene, Mariane Amir

J Bras Pneumol.2003;29(4):178-181

4 - Spirometric values in children and adolescents with short stature

Valores espirométricos de crianças e adolescentes com baixa estatura

Naiza Alessandra Dorneles, Nelson Augusto Rosário Filho, Carlos Antônio Riedi, Margareth Cristina Boguszewski, João Adriano de Barros

J Bras Pneumol.2003;29(4):182-187

5 - Airway inflammation in steroid-naïve asthmatics: characteristics of induced sputum

Inflamação das vias aéreas em asmáticos virgens de tratamento com esteróides: características do escarro induzido

Simone Van de Sande Lee, Marcia Margaret Menezes Pizzichini, Leila John Marques, Samira Cardoso Ferreira, Emilio Pizzichini

J Bras Pneumol.2003;29(4):188-195

6 - Relationship between functional and X-ray alterations in patients with cystic fibrosis

Relação entre alterações funcionais e radiológicas em pacientes com fibrose cística

Andréia Kist Fernandes, Felipe Mallmann, Ângela Beatriz John, Carlo Sasso Faccin, Paulo de Tarso Roth Dalcin, Sérgio Saldanha Menna Barreto

J Bras Pneumol.2003;29(4):196-201

7 - Mediastinal diseases: clinical and therapeutic aspects

Doenças mediastinais: aspectos clínicos e terapêuticos

Roberto Saad Júnior, Maria Elisa Ruffolo Magliari, Júlio Mott Ancona Lopez

J Bras Pneumol.2003;29(4):202-207

Background: Mediastinal affections are common and encompass a great number of different diagnoses. Objective: To analyze the clinical aspects and the therapeutic response of 114 patients with mediastinal diseases treated at the Thoracic Surgery Department of Santa Casa de São Paulo Hospital, from 1979 and 1997. Method: The patients were grouped according to the benign or malignant nature of the disease, and the two groups were compared regarding gender, age bracket, symptomatology, topography of the lesion, mortality, and response to treatment. Results: Sixty-three patients had neoplasia: 31 benign and 32 malignant. Fifty-one cases were not neoplastic. No difference was found between the groups regarding gender or age bracket. Half of the patients were between 20 and 49 years of age. The anterior mediastinum was the most frequently affected compartment (66 patients), followed by the upper mediastinum (18 patients), the posterior mediastinum (16 patients), and the middle mediastinum (14 patients). The most frequent histological types were: benign thymus diseases (N = 40), mesenchymal tumors (N = 17), lymphomas (N = 15), neural tumors (N = 9), and germ cell tumors (N = 8). Malignant tumors were more frequently symptomatic (91%), and benign tumors were more frequent in asymptomatic patients (92%). The most frequent symptoms were related to myastenia gravis, followed by dyspnea and chest pain. Weight loss, anorexia and fever were significantly more frequent in patients with malignant neoplasias. Conclusions: Regarding the clinical aspects we can state that benign lesions were predominant, that mediastinal diseases were more prevalent in young adults, and that benign lesions were more frequent in asymptomatic patients. Treatment (clinical/surgical) was effective in most patients, benefiting approximately 90% of the patients with benign affections and 45% of the patients with malignant tumors. In 73% of the benign affections, surgical treatment was capable of achieving the cure. Mortality resulting from complications was 1.75%.

Keywords: Key words - Mediastinum. Mediastinal disease/epidemiology. Mediastinal neoplasms.

8 - Comparing peak and sustained values of maximal respiratory pressures in healthy subjects and chronic pulmonary disease patients

Comparação entre os valores de pico e sustentados das pressões respiratórias máximas em indivíduos saudáveis e pacientes portadores de pneumopatia crônica

J Bras Pneumol.2003;29(4):208-212

9 - Development of an experimental model of neutrophilic pulmonary response induction in mice

Desenvolvimento de um modelo experimental de indução de resposta pulmonar neutrofílica em camundongos

Leonardo Araújo Pinto, Camila Camozzato, Monique Avozani, Denise Cantarelli Machado, Marcus Herbert Jones, Renato Tetelbom Stein, Paulo Márcio Condessa Pitrez

J Bras Pneumol.2003;29(4):213-216

Case Report

10 - Diffuse alveolar hemorrhage resulting from pauci-immune pulmonary capillaritis

Hemorragia alveolar difusa por capilarite pulmonar pauci-imune

Andreia Salarini Monteiro, Gabriela Addor, David Henrique Nigri, Wilhermo Torres, Carlos Alberto de Barros Franco

J Bras Pneumol.2003;29(4):217-220

11 - Silicosis associated with systemic lupus erythematosus

Associação de silicose e lúpus eritematoso sistêmico

Shirley Castro Holanda, Maria do Socorro T.M. Almeida, Antônio de Deus Filho

J Bras Pneumol.2003;29(4):221-224

Review Article

12 - The value of cytology and pleural biopsy in the differential diagnostic of nonspecific pleural effusions

Valor de citologia e biópsia pleural no diagnóstico diferencial dos derrames pleurais indeterminados

Vera Luiza Capelozzi, Danieli Cheke da Rosa, Aloísio S. Felipe da Silva

J Bras Pneumol.2003;29(4):225-234

13 - Lung tissue remodeling in the acute respiratory distress syndrome

Remodelamento do tecido pulmonar na síndrome do desconforto respiratório agudo

Alba Barros de Souza, Flavia Brandão dos Santos, Elnara Marcia Negri, Walter Araujo Zin, Patricia Rieken Macedo Rocco

J Bras Pneumol.2003;29(4):235-245

Upgrading

14 - Asma grave: uma questão de prescrição ou de diagnóstico?

Afrânio Kritski

J Bras Pneumol.2003;29(4):248-250

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