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Search for: Efeito broncodilatador do salbutamol inalado através de espaçadores com e sem tratamento antiestático

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Original Article

Spirometry with bronchodilator test: effect that the use of large-volume spacers with antistatic treatment has on test response

Prova broncodilatadora na espirometria: efeito do uso de espaçador de grande volume com tratamento antiestático na resposta ao broncodilatador

Flávia de Barros Araújo, Ricardo de Amorim Corrêa, Luis Fernando Ferreira Pereira, Carla Discacciati Silveira, Eliane Viana Mancuso, Nilton Alves de Rezende

J Bras Pneumol.2011;37(6):752-758

Effects of salbutamol delivered by dry-powder inhaler on methacholine-induced bronchoconstriction

Efeito do salbutamol liberado através de inalador de pó seco sobre o broncoespasmo induzido por metacolina

Adalberto Sperb Rubin, Liliana G Pelegrin,Christiano Perin, Maurício Roux Leite, Luiz Carlos Corrêa da Silva

J Bras Pneumol.2004;30(3):195-200

Background: Short-acting b2 agonists delivered by metered-dose inhaler (MDIs) are the drugs usually used for the reversal of methacholine-induced bronchoconstriction. The b2 agonists that are delivered by dry-powder inhaler (DPI) can be an efficacious option. Objective: To evaluate the effectiveness and speed of action of salbutamol delivered by DPI (Pulvinal; Butoventâ), in comparison to salbutamol delivered by MDI, in reversing methacholine-induced bronchoconstriction. Method: Sixty successive methacholine-induced bronchoconstriction patients who presented a decrease of at least 20% in forced expiratory volume (FEV1) were evaluated prospectively. Of these 60 patients, we randomized 30 (first group) to receive 200 mcg of salbutamol by MDI and 30 (second group) to receive 200 mcg of salbutamol by DPI (Pulvinal). Both drugs were administered with the objective of reversing bronchoconstriction during the final phase of a bronchoprovocation test. The FEV1 values obtained at 1 and 5 minutes after bronchodilator administration were evaluated. Results: The groups were comparable in gender distribution, age, weight, dose level provoking a 20% drop in FEV1 (first group: 1.3 mg; second group: 1.19 mg; p = 0.79) and post-methacholine FEV1 (first group: 2.03 l; second group: 1.99 l; p = 0.87), with no statistically significant differences between the two groups. In the first group (MDI), the mean increase in FEV1 was 16.2% (at 1 minute) and 22.2% (at 5 minutes), and in the second group (DPI) it was 17% (at 1 minute) and 23.6% (at 5 minutes). There was no statistically significant difference between the groups (p = 0.8). Conclusion: The b2-agonists delivered by DPI (Pulvinal) present the same bronchodilator efficacy and speed of action as do those delivered by the more traditional MDI method.

Keywords: Asthma. Bronchodilator agents/administration & dosage. Albuterol/administration & dosage. Methacholine chloride/administration & dosage. Respiratory therapy/methods. Administration, inhalation/methods. Prospective studies.

The bronchodilatory effect of salbutamol administered through spacers with and without antistatic treatment

Efeito broncodilatador do salbutamol inalado através de espaçadores com e sem tratamento antiestático

Luiz Eduardo Mendes-Campos, Clarissa Marina Biagioni

J Bras Pneumol.2001;27(5):249-254

Comparative study between technical use, immediate bronchodilation, and adverse effects of the terbutaline turbuhaler and salbutamol (albuterol) in asthmatic patients

Estudo comparativo entre a técnica de uso, efeito broncodilatador e efeitos adversos imediatos de terbutalina via "Turbuhaler" e salbutamol via aerossol em asmáticos

Luiz Fernando F. Pereira, Nelson Morrone

J Bras Pneumol.1997;23(4):167-173

Editorial

Jornal de Pneumologia 1995-1998

Jornal de Pneumologia 1995-1998

Carlos Alberto de Castro Pereira1

J Bras Pneumol.2015;41(5):399

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J Bras Pneumol.2024;50(3):.

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J Bras Pneumol.2024;50(4):edital2025

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J Bras Pneumol.2024;50(5):.

Brief Communication

Heterogeneidade de resposta por IFN-γ a cepas clínicas de Mycobacterium tuberculosis em humanos

Heterogeneidade de resposta por IFN-γ a cepas clínicas de Mycobacterium tuberculosis em humanos

Vinícius Ribeiro Cabral, Cláudia Ferreira de Souza, Fernanda Luiza Pedrosa Guimarães, Maria Helena Feres Saad

J Bras Pneumol.2010;36(4):

Editorial

Jornal Brasileiro de Pneumologia: forty years of history

Jornal Brasileiro de Pneumologia: quarenta anos de história

Manuel Lopes dos Santos

J Bras Pneumol.2015;41(5):397

Jornal Brasileiro de Pneumologia: 40 years of tradition

Jornal Brasileiro de Pneumologia: 40 anos de tradição

Nelson Morrone

J Bras Pneumol.2015;41(5):398

Gratitude for my time at the Jornal de Pneumologia

Gratidão pelo Jornal de Pneumologia que vivi

Thais Helena Abrahão Thomaz Queluz1

J Bras Pneumol.2015;41(5):400

My time at the Jornal Brasileiro de Pneumologia

O Jornal Brasileiro de Pneumologia que eu vivi

José Baddini-Martinez¹

J Bras Pneumol.2015;41(5):402

Index of Issues

Índice remissivo de assuntos do volume 44 (1-6) 2018

Índice remissivo de assuntos do volume 44 (1-6) 2018

J Bras Pneumol.2018;44(6):533-534

Index of Authors

Índice remissivo de autores do volume 44 (1-6) 2018

Índice remissivo de autores do volume 44 (1-6) 2018

J Bras Pneumol.2018;44(6):535-538

List of reviewers

Relação de revisores do volume 44 (1-6) 2018

Relação de revisores do volume 44 (1-6) 2018

J Bras Pneumol.2018;44(6):539-542

Brief Communication

Drug resistance in Mycobacterium tuberculosis strains isolated from sputum samples from symptomatic outpatients - Complexo de Manguinhos, Rio de Janeiro, Brazil

Resistência a drogas em cepas de Mycobacterium tuberculosis isoladas de amostras de escarro de pacientes ambulatoriais sintomáticos - Complexo de Manguinhos, Rio de Janeiro, Brasil

Joycenea Matsuda Mendes, Maria Cristina Lourenço, Rosa Maria Carvalho Ferreira, Leila de Souza Fonseca, Maria Helena Feres Saad

J Bras Pneumol.2007;33(5):579-582

Original Article

Risk for Mycobacterium tuberculosis infection among medical students at the Universidade Federal do Rio de Janeiro Faculdade de Medicina

Risco de infecção pelo Mycobacterium tuberculosis entre alunos da Faculdade de Medicina da Universidade Federal do Rio de Janeiro

Vania Maria Carneiro da Silva, Antônio José Ledo Alves da Cunha, Afrânio Lineu Kritski

J Bras Pneumol.2004;30(5):459-466

Prevalence and severity of asthma symptoms in school-age children in the city of Duque de Caxias, Rio de Janeiro, Brazil

Prevalência e gravidade de sintomas relacionados à asma em escolares e adolescentes no município de Duque de Caxias, Rio de Janeiro

José Laerte Boechat, José Luiz Rios, Clemax Couto Sant'Anna, Alfeu Tavares França

J Bras Pneumol.2005;31(2):111-117

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