Marcia Margaret Menezes Pizzichini1, Regina Maria de Carvalho-Pinto2, José Eduardo Delfini Cançado3, Adalberto Sperb Rubin,4,5, Alcindo Cerci Neto6,7, Alexandre Pinto Cardoso8, Alvaro Augusto Cruz9,10, Ana Luisa Godoy Fernandes11, Daniella Cavalet Blanco12, Elcio Oliveira Vianna13, Gediel Cordeiro Junior14,15, José Angelo Rizzo16, Leandro Genehr Fritscher12, Lilian Serrasqueiro Ballini Caetano11, Luiz Fernando Ferreira Pereira17, Marcelo Fouad Rabahi18, Maria Alenita de Oliveira19, Marina Andrade Lima20, Marina Buarque de Almeida21, Rafael Stelmach2, Paulo Márcio Pitrez22, Alberto Cukier2

J Bras Pneumol.2020;46(1):e20190307

Editorial

November 18: World COPD Day 2020. Is it a date to celebrate?

18 de novembro de 2020: Dia Mundial da DPOC. Uma data para comemorar?

Diane Rezende Batista1a, Liana Sousa Coelho1a, Suzana Erico Tanni1a

J Bras Pneumol.2020;46(6):e20200575

Letters to the Editor

COVID-19 morbidity and mortality in 2020: the case of the city of Rio de Janeiro

Morbidade e mortalidade por COVID-19 em 2020: o caso da cidade do Rio de Janeiro

Nádia Cristina Pinheiro Rodrigues1,2, Mônica Kramer de Noronha Andrade1, Denise Leite Maia Monteiro3, Valéria Teresa Saraiva Lino1, Inês do Nascimento Reis1, Vera Cecília Frossard1, Gisele O'Dwyer1

J Bras Pneumol.2020;46(5):e20200341

Editorial

Revisiting 2019, setting goals for 2020, and reflecting upon open science

Revisitando 2019, projetando 2020 e refletindo sobre a ciência aberta

Bruno Guedes Baldi1,2

J Bras Pneumol.2020;46(1):e20190431

Letters to the Editor

Spatiotemporal evolution of case fatality rates of COVID-19 in Brazil, 2020

Evolução espaçotemporal da letalidade por COVID-19 no Brasil, 2020

Carlos Dornels Freire de Souza1, João Paulo Silva de Paiva1, Thiago Cavalcanti Leal1, Leonardo Feitosa da Silva1, Lucas Gomes Santos1

J Bras Pneumol.2020;46(4):e20200208

Case Report

Pneumothorax as a complication of lung volume recruitment

Pneumotórax como complicação associada ao recrutamento do volume pulmonar

Erik J.A. Westermann, Maurice Jans, Michael A. Gaytant, John R. Bach, Mike J. Kampelmacher

J Bras Pneumol.2013;39(3):382-386

Index of Issues

Índice remissivo de assuntos do volume 44 (1-6) 2018

J Bras Pneumol.2018;44(6):533-534

Index of Authors

Índice remissivo de autores do volume 44 (1-6) 2018

J Bras Pneumol.2018;44(6):535-538

Original Article

Low tidal volume mechanical ventilation and oxidative stress in healthy mouse lungs

Ventilação mecânica com baixo volume corrente e estresse oxidativo em pulmões saudáveis de camundongos

Karla Maria Pereira Pires, Adriana Correa Melo, Manuella Lanzetti, Natália Vasconcelos Casquilho, Walter Araújo Zin, Luís Cristóvão Porto, Samuel Santos Valença

J Bras Pneumol.2012;38(1):98-104

Lung volume reduction surgery in an experimental rat model of emphysema

Cirurgia de redução do volume pulmonar em modelo experimental de enfisema em ratos

Laerte Brasiliense Fusco, Marcelo Heleno Fonseca, Paulo Manuel Pêgo-Fernandes, Rogério Pazetti, Vera Capelozzi, Fabio Biscegli Jatene, Sergio Almeida Oliveira

J Bras Pneumol.2005;31(1):

Background: Lung volume reduction surgery may be a viable treatment alternative for emphysema patients suffering from severe respiratory insufficiency. Objectives: To evaluate functional and morphological aspects of emphysematous rat lungs, prior to and following lung volume reduction surgery. Method: Wistar rats were divided into two experimental groups (papain without surgery and papain with surgery) and three control groups (saline without surgery, saline with surgery and papain without mechanical ventilation). After approximately 40 days of endotracheal instillation of papain or saline solution, animals in the papain with surgery and saline with surgery groups were submitted to bilobectomy of the middle lobes by right thoracotomy along the posterior border of the superior vena cava. After 1 week, the same animals were submitted to a mechanical ventilation study, which involved measurement of lung elasticity and airway resistance. For all of the animals studied, lung tissue was analyzed in order to determine alveolar diameter and the elastic fiber quantity. Results: Morphometric analysis revealed higher mean alveolar diameter in the lungs of all animals exposed to papain as compared to those exposed to saline. Elastic fiber counts in the alveolar septa of animals treated with papain were lower than those of animals receiving saline. In the animals submitted to bilobectomy and papain, lung elasticity was greater than in those receiving papain without surgery and was statistically equal to that seen in animals receiving saline (with or without surgery). Conclusion: In the respiratory systems of animals with pulmonary emphysema submitted to lung volume reduction by bilobectomy, the capacity for elastic recoil returned to values equivalent to those of the control group animals.

Keywords: Key words: Pulmonary emphysema. Papain/drugs efects. Case-control studies. Disease models, animal. Respiratory mechanics/drugs efects. Lung/sugery. Lung/anatomy & histology.

Editorial

Understanding the link between interstitial lung disease and obstructive sleep apnea: is lung volume involved?

Pedro Rodrigues Genta1, Paulo Mateus Madureira Soares Mariano1

J Bras Pneumol.2024;50(5):e20240356

Forced expiratory volume in one second and bronchodilator response in chronic obstructive pulmonary disease - a needless ritual?

Volume expiratório forçado no primeiro segundo e resposta a broncodilatador em doença pulmonar obstrutiva crônica - um ritual inútil?

Carlos Alberto de Castro Pereira

J Bras Pneumol.2005;31(5):4-6

Original Article

Radiological profile of the ideal candidate for lung volume reduction surgery to treat emphysema: a systematic review

Perfil radiológico do candidato ideal à cirurgia redutora de volume pulmonar no enfisema: uma revisão sistemática

Paula Antonia Ugalde Figueroa, Martha Silvia Martinez-Silveira, Eduardo Ponte, Aquiles Camelier, Jorge L. Pereira-silva

J Bras Pneumol.2005;31(3):197-204

Cervical computed tomography in patients with obstructive sleep apnea: influence of head elevation on the assessment of upper airway volume

Tomografia computadorizada cervical em pacientes com apneia obstrutiva do sono: influência da elevação postural na avaliação do volume das vias aéreas superiores

Fábio José Fabrício de Barros Souza1, Anne Rosso Evangelista2, Juliana Veiga Silva2, Grégory Vinícius Périco3, Kristian Madeira4,5

J Bras Pneumol.2016;42(1):55-60

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