Rosane Rodrigues Martins, Edson Marchiori, Sérgio Lopes Viana,
Luiz Sérgio Pereira Grillo Júnior, Vera Luiza Capelozzi, Laércio Moreira Valença
The authors report the case of a female patient who developed chronic eosinophilic pneumonia secondary to long-term use of nitrofurantoin
for prophylaxis of recurrent urinary tract infections due to urethral stenosis. On high-resolution computed tomography scans, the pulmonary
reaction to nitrofurantoin most commonly manifests as an interstitial-alveolar pattern in both lung bases. However, in this case, the
alterations were most pronounced in the periphery of the upper lobes. In itself, this tomographic profile is strongly indicative of chronic
eosinophilic pneumonia. The patient had previously been submitted to an open lung biopsy. The diagnosis of chronic eosinophilic pneumonia
was confirmed through a review of the biopsy.
Keywords: Pneumonia; Pulmonary eosinophilia; Nitrofurantoin/adverse effects; Tomography, X-ray computed.