Gustavo Chatkin, Mauríco Pipkin, José Antonio Figueiredo Pinto,
Vinicius Duval da Silva, José Miguel Chatkin
J Bras Pneumol.2008;34(7):528-531
Amyloidosis is a disease characterized by extracellular deposition of fibrillar protein in organs and tissues. Primary tracheal amyloidosis is rare. We report here a case of a 55-year-old man with tracheal amyloidosis hospitalized for acute respiratory insufficiency and with a history of recent episodes of pneumonia. Chest X-ray and chest computed tomography showed tracheal obstruction due to a tumor. A passage was created in order to relieve the symptoms. Histological examination (Congo red staining) revealed amyloid deposits but no evidence of neoplasia. Although this is a rare clinical condition, its importance is discussed regarding the differential diagnosis of tracheal tumors and the repercussions for therapeutic decision-making.
Keywords: Amyloidosis; Respiratory insufficiency; Congo red; Airway obstruction.