Alexandre Heitor Moreschi, Amarilio Vieira de Macedo Neto,
Gilberto Venossi Barbosa, Mauricio Guidi Saueressig
Objective: To evaluate the impact of an aggressive treatment approach using muscle flaps or omentopexy in infections of the sternum
and anterior mediastinum following sternotomy on mortality, as compared to that of a conservative treatment approach. Methods: Data
were collected prior to, during and after the surgical procedures. Group A (n = 44) included patients submitted to conservative treatment-
debridement together with resuture or continuous irrigation with polyvinylpyrrolidone-iodine solutions, or even with second-intention
wound healing (retrospective data). Group B (n = 9) included patients in whom infection was not resolved with conservative treatment, and
who therefore underwent aggressive treatment (intermediate phase). Group C (n = 28) included patients primarily submitted to aggressive
treatment (prospective data). Results: Postoperative hospital stays were shorter in the patients submitted to aggressive treatment (p < 0.046).
There were 7 deaths in group A, 1 in group B, and 2 in group C. However, the classical level of significance of α = 0.05 was not reached.
Conclusion: Aggressive treatment also proved to be effective when the infection was not resolved with conservative treatment. These
findings demonstrate that the proposed treatment provides excellent results.
Keywords: Surgical flaps; Osteomyelitis; Mediastinitis; Thoracic surgery.